日本の寒地，北海道における2030年代の水稲生育への温暖化の影響予測とその対応(日语原文)

北海道では1980年代から2010年代まで，水稲圃場栽培期間である5–9月の気温は年代とともに上昇した。そこで，直近の2010年代（2010—2019年平均）と比べて， 2つの2030年代の予測気象から，既報の関係式より水稲生育を予測した。その結果，2030年代では2010年代に比べ，限界移植日（移植早限）が水稲栽培17地域の平均で8～9日早い。また，早限出穂期が1～5日早く，晩限出穂期が1～5日遅く，安全出穂期間が2～10日長い。出穂期は1～3日早い。出穂期から晩限出穂まで2～9日長いため，遅延型冷害の発生がやや少ない。生育期別気象は，出穂前24日以降30日間では生育が早いため平均気温が同じかやや低い。出穂前10日以降40日間および出穂期以降40日間では平均気温がやや高く，日射量はやや少ない。そのため，玄米収量は96～98％とやや低く，潜在収量性を示す気候登熟量示数は同じである。障害不稔発生に関係する穂ばらみ期冷害危険期の平均気温はわずかに低いかほぼ同じであるため，冷害発生の危険性は残る。一方，不稔発生をもたらす低温域の出現頻度には，地域間で差異がある。精米蛋白質含有率は同じであるが，アミロース含有率はやや低く，やや良食味である。米粒外観品質では被害粒歩合と着色粒歩合は一定の傾向がなく，未熟粒歩合はやや高い。精米白度は同じであるが，玄米白度はやや高い。以上の予測に対する技術的対応方向を示した。     

Molecular Characteristics of Amyloid Precursor Protein (APP) and Its Effects in Cancer

Amyloid precursor protein (APP) is a type 1 transmembrane glycoprotein, and its homologs amyloid precursor-like protein 1 (APLP1) and amyloid precursor-like protein 2 (APLP2) are highly conserved in mammals. APP and APLP are known to be intimately involved in the pathogenesis and progression of Alzheimer’s disease and to play important roles in neuronal homeostasis and development and neural transmission. APP and APLP are also expressed in non-neuronal tissues and are overexpressed in cancer cells. Furthermore, research indicates they are involved in several cancers. In this review, we examine the biological characteristics of APP-related family members and their roles in cancer.     

Synthesis and performance evaluation of a new drag reducer based on acrylamide/12-allyloxydodecyl acid sodium

Hydraulic fracturing with slickwater is a field-proven stimulation technology used in tight reservoirs. Because of the high pumping rate associated with slickwater fracturing, drag reduction (DR) is critical in minimizing pressure drop and the success of oilfield operations. In this paper, a new type of drag reducer (SPR) was synthesized with acrylamide and 12-allyloxydodecyl acid sodium, and its drag reduction performance was evaluated. The results showed that the new drag reducer features low molecular weight, fast-dissolving rate and low interfacial tension. The algorithm of estimating the drag reduction rate of non-Newtonian fluid SPR was proposed and validated. Empirical or semianalytical models for estimating the friction ratio (σ) or friction factor (λ or f) were used to simulate the turbulence behavior of the SPR drag reducer under different Reynolds numbers (Re). The modified Virk's correlation could accurately model the turbulent behavior of the SPR drag reducer. A unified calculation formula was established in this study for different pipe diameters.     

Effects of fibers and conventional reinforcement contents on fibers scaterring in prismatic bars

This paper presents results from a second stage of an experimental study of the dependence of steel fibers distribution along RFC prismatic specimens on the conventional reinforcement ratio and on the total amount of fibers in the concrete mix. The experimental program included two types of prismatic specimens with 30- and 60- kg/m³ of hooked-end steel fibers. Each specimen was sawed into equal segments and the numbers of fibers appearing at the cross-sections were counted and used for a further statistical analysis. This analysis comprised calculations of the average value and standard deviation of a non-dimensional variable, which represents the distribution of the total steel along the specimen. They were used to calibrate a theoretical model, which had been previously proposed by the authors. The test results showed reasonable to good agreement with the theoretical model. A comparison between the results of the 30- and 60-kg/m³ fibers shows that as the conventional reinforcement ratio increases, the standard deviations for the different mixtures approach each other.     

高泉背斜地层压力测井多参数综合解释与异常高压成因

目前国内外地层压力测井解释方法较多,但大多数方法基于欠压实沉积理论并局限于单一的地层岩性,尤其是针对盆地边缘山前深层构造,单一测井参数确定地层压力误差较大,且无法解释沉积压实机制以外的异常高压。为此,将多种异常高压机制相关的测井参数进行综合解释,建立适合山前复杂构造的地层压力测井多参数计算模型,评价准噶尔盆地南缘高泉背斜高探1井的地层压力剖面,其计算结果与钻井实测数据吻合,相对误差小于3.00%.同时,基于原始沉积加载—卸载过程力学原理,利用地层压力测井多参数分析判别出高泉背斜深层各层系异常高压的形成机制。     

宁夏红寺堡盆地隐伏古隆起成因机制及其对区域沙漠化的影响

目前对于青藏高原东北缘活动构造研究多集中于活动断裂带的活动性,而对夹持于其间的沉积盆地构造格架及活动性研究甚少。以夹持于烟筒山断裂与牛首山—罗山断裂之间的宁夏红寺堡盆地为研究对象,采用重力资料重处理解译、音频大地电磁测深(AMT)和地震勘探相结合,揭示红寺堡盆地隐伏构造特征,并进一步采用盆山一体化思路分析隐伏构造的成因机制及其对区域沙漠化的控制作用。结果表明:青藏高原在中新世末发生强烈的NE向推挤、扩展和隆升,红寺堡盆地由坳陷盆地转变为挠曲盆地; 在青藏高原NE向扩展的影响下,烟筒山断裂发生强烈的逆冲作用,古生代—中生代基底逆冲于古近系—新近系之上,受构造变形影响的最新地层为中新统彰恩堡组; 红寺堡盆地内的隐伏古隆起呈NW—SE向,与烟筒山构造带具有相同的构造动力学背景,受青藏高原NE向扩展影响形成于中新世末,并且至今仍具有活动性; 隐伏古隆起周缘断裂的活动破坏了地表稳定性、蓄水能力和地表植被,导致区域沙漠化呈现有规律的NW—SE向带状展布。该研究成果对于宁夏红寺堡盆地区域稳定性评价及沙漠化的综合治理具有现实指导意义。     

The influence of national culture on responsible innovation: A case of CO2 utilisation in Indonesia

Responsible innovation (RI) offers a promising step towards a more responsible adoption of innovations, such as new and emerging technologies. However, how RI would be practised in different cultural contexts and settings is still less studied, especially in the context of developing countries. Taking the utilisation of CO₂ in Indonesia as an empirical case, the purpose of this paper is to explore this issue through examining the influence of key characteristics of Indonesia's national culture on core dimensions of RI: anticipation, reflexivity, deliberation, responsiveness and participation. The different RI dimensions are applied in practice in a focus group discussion (FGD) and a round of interviews with different stakeholders that explored CO₂ utilisation in the country. Hofstede's classification of national cultural dimensions is used to single out key focus points for attention in these RI processes in the Indonesian context. The results from the experiment illustrate that culture matters in the application of RI dimensions in practice. In the sense that in order for RI to work well, the governance of core RI processes such as participation and deliberation has to be adjusted to social norms of what is considered legitimate, desirable and good behaviour. These norms differ across societies. The findings further suggest ways of applying RI dimensions in practice.     

Fair‐Weather Friends: Evidence of Lipoxin Dysregulation in Neurodegeneration

Lipoxins (LXs) are autacoids, specialized proresolving lipid mediators (SPMs) acting locally in a paracrine or autocrine fashion. They belong to a complex superfamily of dietary small polyunsaturated fatty acid (PUFA)–metabolites, which direct potent cellular responses to resolve inflammation and restore tissue homeostasis. Together, these SPM activities have been intensely studied in systemic inflammation and acute injury or infection, but less is known about LX signaling and activities in the central nervous system. LXs are derived from arachidonic acid, an omega‐6 PUFA. In addition to well‐established roles in systemic inflammation resolution, they have increasingly become implicated in regulating neuroinflammatory and neurodegenerative processes. In particular, chronic inflammation plays a central role in Alzheimer's disease (AD) etiology, and dysregulated LX production and activities have been reported in a variety of AD rodent models and clinical tissue samples, yet with complex and sometimes conflicting results. In addition, reduced LX production following retinal injury has been reported recently by the authors, and an intriguing direct neuronal activity promoting survival and homeostasis in retinal and cortical neurons is demonstrated. Here, the authors review and clarify this growing literature and suggest new research directions to further elaborate the role of lipoxins in neurodegeneration.     

儿童用品TBT通报数据可视化预警研究

探索采用数据可视化技术分析儿童用品TBT通报数据,以可视化图形图像呈现通报热点并揭示趋势信息,提出对策与建议,助力为儿童用品产业升级、TBT预警数据分析和信息传播工作提供新思路,提高中小企业的国外市场准入机会。